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GW 441756

CAS No. : 504433-23-2

MCE 國際站：GW 441756

產(chǎn)品活性：GW 441756 是一種高效特異性神經(jīng)生長因子 (NGF) 受體酪氨酸激酶 a (TrkA) 抑制劑 (IC₅₀=2 nM)，可消除 BmK NSPK-induced 神經(jīng)突生長。

研究領(lǐng)域：Neuronal Signaling  |  Protein Tyrosine Kinase/RTK  |  Apoptosis

作用靶點：Trk Receptor  |  Apoptosis

In Vitro: GW-441756 (1 μM; 48 hours; spinal cord neurons cells) abolishs BmK NSPK-induced neurite outgrowth.
?GW-441756 (1 μM; 4 hours; PC12 cells) inhibits nerve growth factor induced neurite outgrowth.

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