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MCE 國(guó)際站:Tulisokibart
品牌:MedChemExpress (MCE)
貨號(hào):HY-P990007
CAS:2648504-55-4
Synonyms:PRA023; PRA-023
純度:0.99
存儲(chǔ)條件:請(qǐng)按照分析證書中建議的條件儲(chǔ)存產(chǎn)品。
運(yùn)輸條件:使用干冰運(yùn)輸。
產(chǎn)品活性:Tulisokibart (PRA023) 是人源化后的小鼠 IgG1-κ 型抗體,靶向 TNFSF15/TL1A。Tulisokibart 可用于多種炎癥/纖維化疾病的研究,例如克羅恩病 (Crohn's Disease, CD) 和潰瘍性結(jié)腸炎 (ulcerative colitis, UC)。
種屬:Humanized
同型:Human IgG1 kappa
推薦同型對(duì)照抗體:Human IgG1 kappa, Isotype Control
熱銷產(chǎn)品:R-spondin 3, Human (125aa, HEK293, His) | Trigonelline | Triciribine | Codrituzumab | Coenzyme Q9 | Fosmidomycin sodium salt | WSP-1 | Stearoylcarnitine | LEP(116-130)(mouse) | Prazosin (hydrochloride)
Trending products:Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent Dye | PROTAC | Isotope-Labeled Compounds | Oligonucleotides
參考文獻(xiàn):
[1]. Tulisokibart. IMGT/mAb-DB.
[2]. Feagan B G, Sands B, Siegel C A, et al. DOP87 The Anti-TL1A Antibody PRA023 Demonstrated Proof-of-Concept in Crohn’s Disease: Phase 2a APOLLO-CD Study Results[J]. Journal of Crohn's and Colitis, 2023, 17(Supplement_1): i162-i164.
[3]. B Sands, et al. OP40 PRA023 Demonstrated Efficacy and Favorable Safety as Induction Therapy for Moderately to Severely Active UC: Phase 2 ARTEMIS-UC Study Results, Journal of Crohn's and Colitis, Volume 17, Issue Supplement_1, February 2023, Pages i56–i59
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