MCE 的所有產(chǎn)品僅用作科學(xué)研究或藥證申報,我們不為任何個人用途提供產(chǎn)品和服務(wù)。
MCE 國際站:Hydrocortisone
品牌:MedChemExpress (MCE)
CAS:50-23-7
純度:0.9991
貨號:HY-N0583
中文名稱:氫化可的松;可的索;可的唑;皮質(zhì)醇;氫可的松;17-羥基皮質(zhì) (甾) 酮;皮質(zhì)甾醇;氫化皮質(zhì)素
Synonyms:氫化可的松; Cortisol
存儲條件:4°C,避光保存 *溶劑中:-80°C,6 個月;-20°C,1 個月(避光保存)
運輸條件:美國大陸的室溫;其他地方可能有所不同。
產(chǎn)品活性:Hydrocortisone (Cortisol) 是腎上腺皮質(zhì)分泌的類固醇激素或糖皮質(zhì)激素。
細胞實驗:將細胞接種于膠原蛋白IV包被的Transwell小室上,用于六孔板(直徑24mm,膜材料:聚對苯二甲酸乙二醇酯(PET),0.4μm孔徑,孔密度1.6×106cm2),密度為每孔2.5×104細胞cm2。當它們在第5天達到匯合時,將不同的實驗組細胞轉(zhuǎn)移到含有少量FCS的分化培養(yǎng)基中,并根據(jù)指示用TNFα或氫化可的松處理。MCE尚未獨立證實這些方法的準確性。它們僅供參考。
IC50 & Target:Human Endogenous Metabolite
熱銷產(chǎn)品:CPTH2 | Pirinixic acid | Deoxycholic acid | Deferasirox | Methyl cellulose | Fibronectin, Human | Coenzyme Q10 | 5-Aminosalicylic Acid | GIP, human (TFA) | Campesterol
Trending products:Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent Dye | PROTAC | Isotope-Labeled Compounds | Oligonucleotides
參考文獻:
[1]. F?rster C, et al. Differential effects of hydrocortisone and TNFalpha on tight junction proteins in an in vitro model of the human blood-brain barrier. J Physiol. 2008 Apr 1;586(7):1937-49.
[2]. Bellinghausen I, et al. Inhibition of human allergic T-cell responses by IL-10-treated dendritic cells: differences from hydrocortisone-treated dendritic cells. J Allergy Clin Immunol. 2001 Aug;108(2):242-9.
[3]. Chappell D, et al. Hydrocortisone preserves the vascular barrier by protecting the endothelial glycocalyx. Anesthesiology. 2007 Nov;107(5):776-84.
立即詢價
您提交后,專屬客服將第一時間為您服務(wù)