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Source

Rabbit

Applications

WB,ELISA

Reactivity

Human

Dilution

WB: 1:500 - 1:2000. ELISA: 1:5000. Not yet tested in other applications.

Storage

-20°C/1 year

Specificity

Arginase II Polyclonal Antibody detects endogenous levels of Arginase II protein.

Source/Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen

The antiserum was produced against synthesized peptide derived from human ARG2. AA range:305-354

Uniprot No

P78540

Alternative names

ARG2; Arginase-2; mitochondrial; Kidney-type arginase; Non-hepatic arginase; Type II arginase

Form

Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Clonality

Polyclonal

Isotype

IgG

Background

arginase 2(ARG2) Homo sapiens Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exists (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type II isoform encoded by this gene, is located in the mitochondria and expressed in extra-hepatic tissues, especially kidney. The physiologic role of this isoform is poorly understood; it is thought to play a role in nitric oxide and polyamine metabolism. Transcript variants of the type II gene resulting from the use of alternative polyadenylation sites have been described. [provided by RefSeq, Jul 2008],

Other

ARG2, Arginase-2 mitochondrial; Kidney-type arginase; Non-hepatic arginase; Type II arginase

Mol.Wt (Da)

38578

Concentration

1 mg/ml